Key Takeaways

  • The top 25 medical office space markets in the U.S. grew 13% since 2012, adding more than 52.7 million square feet.
  • Los Angeles, Dallas-Fort Worth & Houston were top medical office space markets — nearly one-quarter of all space added in the last decade were in these markets.
  • Minneapolis-St. Paul’s medical office space market grew the most at 24%, adding 3 million square feet — almost as much as was added in Los Angeles.
  • LA & Manhattan added the largest medical office buildings in the last 10 years at 820,000 and 750,000 square feet, respectively.
  • New Jersey & San Antonio are set to deliver the largest medical office buildings of those currently in the pipeline.

Medical office buildings (MOBs) have proven to be a particularly resilient asset class within commercial real estate through the pandemic. That’s because most MOB tenants require these spaces to treat patients in person, thereby providing a more stable tenant base for the asset class. But even though this is a more stable asset class, there’s an undersupply of state-of-the-art medical office buildings. The buildings themselves are more complicated to operate than traditional office space — and even more complicated to build. But if CBRE’s recent announcement to expand its medical office building portfolio is any indication, investment in these facilities is growing.

So, using data provided by CRE research and listing platform CommercialEdge, we analyzed the last decade of medical office building construction activity — between 2012 and 2021 — to see how this asset class had blossomed into the spotlight for CRE investment firms. Specifically, we looked at 25 major commercial real estate markets, analyzing how deliveries and sales volumes in these markets had progressed throughout the last 10 years.

LA, Dallas & Houston Are Nation’s Top MOB Markets

The total MOB square footage across the top 25 medical office markets in the country topped 470 million in 2021, which is 13% larger than it was 10 years ago and represents an addition of more than 52.7 million square feet combined.

Los Angeles led the country for MOB square footage with more than 1,000 medical office buildings totaling more than 41 million square feet — far more than any other single market in the entire country. However, LA’s medical office market only grew 9% in the last decade — adding 3.48 million square feet and reaching a total 587 buildings.

Meanwhile, Texas’ two largest medical office space markets saw major growth in the medical office sector, as well: The second-largest MOB market in the country was Houston, which added 4.3 million square feet of medical office space in the last 10 years, growing 15% to its current total of 33.2 million square feet. Dallas-Fort Worth’s medical office market saw similar growth — adding 4.6 million square feet, growing 16% since 2012 to its current 33-million-square-foot medical office footprint.

MOB Growth Strongest in Twin Cities & Richmond-Tidewater

Notably, lower-tier markets with aging populations saw some of the most growth in the last 10 years — case in point: the Twin Cities. Minneapolis-St. Paul came in 15th for medical office space in the country with 231 buildings totaling 15.8 million square feet. However, the market has grown nearly 24% since 2012, adding 3 million square feet — almost as much medical square footage as was added in Los Angeles during the same period — as the 65 and older demographic makes up 17% of the population in Minneapolis and is projected to grow to more than 20% by 2038.

And, while Richmond-Tidewater was the 23rd-largest MOB market in the country by square footage, it, too, has grown rapidly in the last 10 years: Of Richmond-Tidewater’s 11.3 million square feet of medical office space, more than 2 million was built since 2012 — a market growth of 22%.

In the Midwest, Chicago’s medical office space market was comprised of 28.8 million square feet across 427 buildings — the fourth-largest MOB market in the country. The sprawling Windy City added more than 4.3 million square feet of medical office space in the last 10 years — growing nearly 18% since 2012.

LA & Manhattan Build Largest MOBs in Last 10 Years

While MOBs tend to be smaller than traditional office buildings, it doesn’t mean that they always are. For example, Cedars-Sinai Advanced Health Sciences Pavilion was the largest MOB to be completed in the last 10 years. Delivered in 2013, the 820,000-square-foot Los Angeles medical office building specializes in minimally invasive surgeries, sports medicine, joint replacements and orthopedics.

Across the country, the second- and third-largest MOB deliveries of the last decade were in East Coast markets — Manhattan and Philadelphia. First, the 750,000-square-foot, Upper East Side medical center — the David H. Koch Center for Cancer Care — stands 25 stories above FDR Drive and was completed in 2020. Next, the Buerger Center for Advanced Pediatric Care in Philadelphia was completed in 2015 and added 706,000 square feet of medical office space just south of the University of Pennsylvania.

Smaller MOB Markets Set to Deliver Larger Buildings

The pandemic highlighted the resilience of MOBs — as well as the undersupply of them — and construction of medical offices continues across the country. To that end, New Brunswick, N.J., will add 519,500 square feet of medical office space in a single building in Q1 2024 with the completion of the Jack and Sheryl Morris Cancer Center. Likewise, The Rock at La Cantera is set to be completed in Q3 of next year, adding 500,000 square feet of medical offices to San Antonio.

The next two years will also see three large deliveries across three Midwestern markets: Chicago; Madison, Wis.; and Milwaukee. These three buildings will collectively add more than 1.4 million square feet of state-of-the-art medical office space to the region. Overall, the combined total of the top 10 projects to be delivered by the end of 2024 will be nearly 4.4 million square feet of prime medical office space.


The markets featured in our report are the top 25 medical office space by total square footage in the U.S., according to data compiled by CommercialEdge.

Yearly square footage deliveries and property completion dates are per CommercialEdge data and only include medical office properties larger than 25,000 square feet. The completion date represents the completion of the building itself, not the date it opened to the public.

The latest data update was conducted on August 30, 2022.

While CommercialEdge attempts to ensure the timeliness and accuracy of all provided data, it cannot be guaranteed. Figures for expected deliveries is particularly subject to change as CommercialEdge compiles and ensures the accuracy of property completions.

MarketTotal Medical Office Square FootageTotal Square Feet AddedPercentage Growth
Los Angeles 40,935,210 3,481,5139.30%
Houston 33,221,302 4,317,734 14.94%
Dallas - Fort Worth 33,075,948 4,629,934 16.28%
Chicago 28,828,690 4,313,30317.59%
Washington, D.C. 24,317,954 2,163,7569.77%
Atlanta 23,996,707 2,880,61213.64%
Philadelphia 23,243,961 4,026,83920.95%
Phoenix 21,442,725 1,850,5729.45%
Denver 19,651,630 2,444,19714.20%
Seattle 18,673,586 1,758,26310.39%
Bay Area 17,823,303 1,883,86911.82%
New Jersey 17,405,670 1,108,9996.81%
Detroit 17,265,426 816,7284.97%
Boston 16,785,431 1,392,5499.05%
Minneapolis - St. Paul 15,797,750 3,008,91223.53%
Orange County 13,473,949 851,1416.74%
San Diego 12,649,598 889,6867.57%
Cleveland-Akron 11,862,957 592,4485.26%
Baltimore 11,845,647 1,216,81211.45%
Miami 11,842,122 1,099,36410.23%
Tampa 11,545,540 1,772,90118.14%
Indianapolis 11,488,831 1,428,52614.20%
Richmond-Tidewater 11,277,665 2,012,59321.72%
San Francisco 11,133,850 1,511,80615.71%
Bridgeport - New Haven 11,096,775 1,258,83912.80%