In the last 90 days, 7 listings have been posted online, which means leases most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around sqft. Most properties in this area are close to 6 stories. Most buildings in this area were built in 1960 and are Class B.
Wholesale trade is the dominant industry in this area. Most of the folk of Five Points District work from home. Commuting between 30 and 45 minutes a day is the norm for those who opt to reside in this part of town.