On average, listings lease in the $20's per square foot per year. The Hilton Head Island region is going through a decline in rates. In the last 3 months, the median rate decreased $2 per sqft per year. That's a 7% decline in rent.
In the last 90 days, 14 listings have come on the market, which means spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 64% of the available space in the Hilton Head Island are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,700 sqft. Most buildings in this market are close to 3 stories. Most buildings in this area were built in 1986 and are Class A.