The typical asking rate per listing is in the $20's per square foot per year. The James Island submarket is going through a a rise in rates. In the last 3 months, the median rate went up $1 per sqft per year. That's a 6% increase in rent.
In the last 90 days, 6 listings have come on the market, which means leases might be leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,540 sqft. Most properties in this market are close to 2 floors. Most buildings in this area were built in 1981 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Manufacturing is the dominant industry in this market. Most of the folk of James Island work from home. Commuting around an hour a day is the norm for those who opt to reside in this part of town.