The typical asking rate per listing is in the $20's per square foot per year. The State College region is seeing a an increase in rates. In the last 3 months, the median rate increased $21 per sqft per year. That's a Inf% increase in rent.
In the last 90 days, 3 listings have been made available, which means listings are probably going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 180 sqft. Most properties in this area are approximately 3 stories.