On average, listings lease in the $30's per square foot per year. The Poughkeepsie submarket is seeing a a rise in rates. In the last 3 months, the median rate went up $11 per sqft per year. That's a 50% rise in rent.
In the last 90 days, 4 listings have been made available, which means listings most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,300 sqft. Most properties in this area are close to 3 floors. Most buildings in this market were built in 1966 and are Class A.