Most listings are in the $130's per square foot per year. The Harlem submarket is going through a a rise in rates. In the last 3 months, the median rate increased $133 per sqft per year.
Compared to the rest of the New York City market, the Harlem submarket has greater rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 16 listings have been made available, which means new listings might be going fast. You'll want to be prepared to make an offer immediately. About 100% of the listings in the Harlem are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,400 sqft. Most properties in this market are approximately 5 stories. Most buildings in this market were built in 1920 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Utilities is the dominant industry in this area. Most of the occupants of Harlem work from home. Commuting close to 20 minutes a day is the norm for those who opt to reside in this part of town.