The typical asking rate per listing is in the $40's per square foot per year. The Downtown Santa Fe submarket is going through a a rise in rates. In the last 3 months, the median rate went up $42 per sqft per year.
In the last 90 days, 3 listings have been posted online, which means new availabilities are probably leasing quickly. You'll want to be prepared to tour spaces as quick as possible. About 633% of the available space in the Downtown Santa Fe are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 500 sqft. Most buildings in this market are approximately 2 stories. Most buildings in this region were built in 0 and are Class B.
This region is fairly equally mixed residential and commercial. Professional services is the dominant industry in this market. Most of the folk of Downtown Santa Fe work from home. Commuting between 20 and 25 minutes a day is the norm for those who opt to reside in this part of town.