Most listings are in the $30's per square foot per year. The Boone region is experiencing a a rise in rates. In the last 3 months, the median rate rose $35 per sqft per year.
In the last 90 days, 4 listings have been listed, which means new availabilities are probably leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 180 sqft. Most buildings in this area are around 3 floors. Most buildings in this area were built in 2008 and are Class A.