In the last 90 days, 13 listings have been listed, which means leases most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 200% of the available leases in the South Loop are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,330 sqft. Most properties in this area are close to 3 floors. Most buildings in this area were built in 1982 and are Class B.
This area is fairly equally mixed residential and commercial. Health care is the dominant industry in this area. Commute by bike is the most popular way to get to work amongst South Loop occupants. Commuting between 30 and 45 minutes a day is the norm for those who opt to reside in this part of town.