On average, listings lease in the $10's per square foot per year. The Mission submarket is going through a decline in rates. In the last 3 months, the median rate decreased $6 per sqft per year. That's a 27% decline in rent.
In the last 90 days, 28 listings have been posted online, which means office spaces might be going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,470 sqft. Most buildings in this market are around 2 floors. Most buildings in this market were built in 1972 and are Class B.