On average, listings lease in the $20's per square foot per year. The Manhattan submarket is experiencing a decline in rates. In the last 3 months, the median rate decreased $14 per sqft per year. That's a 38% decline in rent.
In the last 90 days, 10 listings have been posted online, which means spaces might be leasing quickly. You'll want to be prepared to make an offer immediately. About 10% of the listings in the Manhattan are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 390 sqft. Most properties in this area are approximately 1 floors. Most buildings in this region were built in 1984 and are Class A.