Most listings are in the $30's per square foot per year. The Manhattan submarket is going through a a rise in rates. In the last 3 months, the median rate increased $14 per sqft per year. That's a 61% rise in rent.
In the last 90 days, 10 listings have been listed, which means spaces might be going fast. You'll want to be prepared to make an offer immediately. About 60% of the available leases in the Manhattan are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,270 sqft. Most properties in this region are approximately 1 stories. Most buildings in this market were built in 1984 and are Class A.