On average, listings lease in the $20's per square foot per year. The Louisville region is going through a an increase in rates. In the last 3 months, the median rate went up $1 per sqft per year. That's a 7% rise in rent.
In the last 90 days, 22 listings have been posted online, which means spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 5% of the available space in the Louisville are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 4,760 sqft, there are still 0 new listings below 2,000 sqft. Most buildings in this market are around 2 floors. Most buildings in this area were built in 1999 and are Class A.