Most listings are in the $20's per square foot per year. The Littleton region is going through a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 5% decrease in rent.
Compared to the rest of the Denver Metro market, the Littleton submarket has smaller rates, so you should have no trouble finding a great deal in this discounted submarket.
In the last 90 days, 15 listings have been made available, which means spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 7% of the office spaces in the Littleton are subleases, so you will probably have to focus your search on direct office leases. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,850 sqft. Most properties in this region are around 2 floors. Most buildings in this area were built in 1983 and are Class B.