Most listings are in the $40's per square foot per year. The LoDo region is going through a a rise in rates. In the last 3 months, the median rate increased $9 per sqft per year. That's a 21% increase in rent.
In the last 90 days, 31 listings have come on the market, which means spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 13% of the available leases in the LoDo are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 5,720 sqft, there are still 0 office spaces below 2,000 sqft. Most buildings in this region are approximately 7 floors. Most buildings in this area were built in 1963 and are Class B.
This region is fairly equally mixed residential and commercial. Waste services is the dominant industry in this region. Commute by bike is the most popular way to get to work amongst LoDo residents. Commuting around an hour a day is the norm for those who opt to reside in this part of town.