The typical asking rate per listing is in the $20's per square foot per year. The Santa Ana region is experiencing a a rise in rates. In the last 3 months, the median rate rose $5 per sqft per year. That's a 19% increase in rent.
Compared to the rest of the Metropolitan Los Angeles market, the Santa Ana submarket has lower rates, so you should have no trouble finding a great deal in this depreciated submarket.
In the last 90 days, 154 listings have been posted online, so you'll want to check back regularly for new listings. About 3% of the available space in the Santa Ana are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,970 sqft. Most buildings in this region are close to 2 stories. Most buildings in this region were built in 1982 and are Class B.