Most listings are in the $30's per square foot per year. The San Luis Obispo region is seeing a a boost in rates. In the last 3 months, the median rate went up $4 per sqft per year. That's a 15% increase in rent.
In the last 90 days, 26 listings have come on the market, which means new listings might be leasing quickly. You'll want to be prepared to make an offer immediately. About 15% of the listings in the San Luis Obispo are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,020 sqft. Most buildings in this region are around 2 stories. Most buildings in this region were built in 2000 and are Class A.