On average, listings lease in the $20's per square foot per year. The San Leandro region is going through a a boost in rates. In the last 3 months, the median rate went up $4 per sqft per year. That's a 20% rise in rent.
Compared to the rest of the East Bay market, the San Leandro region has lower rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 39 listings have come on the market, which means new listings most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,830 sqft. Most properties in this region are close to 1 stories. Most buildings in this region were built in 1973 and are Class B.