On average, listings lease in the $20's per square foot per year. The Southwest San Francisco region is going through a an increase in rates. In the last 3 months, the median rate went up $25 per sqft per year.
Compared to the rest of the Bay Area market, the Southwest San Francisco region has lower rates, so you should have no trouble finding a great deal in this discounted submarket.
In the last 90 days, 20 listings have been posted online, which means listings most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. About 580% of the available leases in the Southwest San Francisco are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 650 sqft. Most buildings in this region are close to 2 stories. Most buildings in this region were built in 1933 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Finance and insurance are the dominant industries in this area. Most of the occupants of Southwest San Francisco work from home. Commuting around 30 minutes a day is the norm for those who opt to reside in this part of town.