On average, listings lease in the $60's per square foot per year. The Mission District submarket is going through a an increase in rates. In the last 3 months, the median rate rose $5 per sqft per year. That's a 8% increase in rent.
Compared to the rest of the Bay Area market, the Mission District submarket has more expensive rates, and you'll have to negotiate above asking rent to be in this hot submarket.
In the last 90 days, 27 listings have been listed, which means office spaces are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 4% of the available leases in the Mission District are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,500 sqft. Most properties in this region are around 2 stories. Most buildings in this market were built in 1914 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Utilities is the dominant industry in this area. Commute by public transit is the most popular way to get to work amongst Mission District folk. Commuting around 10 minutes a day is the norm for those who opt to reside in this part of town.