On average, listings lease in the $70's per square foot per year. The Lower Nob Hill region is experiencing a a rise in rates. In the last 3 months, the median rate increased $76 per sqft per year.
Compared to the rest of the Bay Area market, the Lower Nob Hill region has higher rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 16 listings have been made available, which means spaces most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. About 50% of the available leases in the Lower Nob Hill are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,260 sqft. Most properties in this market are approximately 4 stories. Most buildings in this market were built in 1915 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this area. Most of the residents of Lower Nob Hill work from home. Commuting approximately 15 minutes a day is the norm for those who opt to reside in this part of town.