Most listings are in the $60's per square foot per year. The Downtown San Francisco-Union Square submarket is going through a an increase in rates. In the last 3 months, the median rate went up $66 per sqft per year.
Compared to the rest of the Bay Area market, the Downtown San Francisco-Union Square region has more expensive rates, and you'll have to negotiate above asking rent to be in this hot submarket.
In the last 90 days, 53 listings have been made available, so you'll want to check back regularly for new listings. About 98% of the office spaces in the Downtown San Francisco-Union Square are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,210 sqft. Most buildings in this area are around 6 stories. Most buildings in this region were built in 1909 and are Class B.
Health care is the dominant industry in this area. Commute by car is the most popular way to get to work amongst Downtown San Francisco-Union Square folk. Commuting between 30 and 45 minutes a day is the norm for those who opt to reside in this part of town.