Most listings are in the $50's per square foot per year. The Cathedral Hill submarket is going through a an increase in rates. In the last 3 months, the median rate went up $51 per sqft per year.
Compared to the rest of the Bay Area market, the Cathedral Hill region has higher rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 2 listings have been posted online, which means office spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 2,800 sqft, there are still 0 spaces below 2,000 sqft. Most properties in this area are close to 5 stories. Most buildings in this area were built in 1950 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Construction is the dominant industry in this area. Commute by bike is the most popular way to get to work amongst Cathedral Hill residents. Commuting between 30 and 45 minutes a day is the norm for those who opt to reside in this part of town.