On average, listings lease in the $20's per square foot per year. The Poway region is experiencing a decline in rates. In the last 3 months, the median rate decreased $6 per sqft per year. That's a 18% decline in rent.
Compared to the rest of the San Diego market, the Poway submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 26 listings have been posted online, which means spaces are probably going fast. You'll want to be prepared to tour spaces as quick as possible. About 8% of the available space in the Poway are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
Even though the median size is 4,130 sqft, there are still 0 office spaces below 2,000 sqft. Most properties in this area are around 2 stories. Most buildings in this market were built in 1999 and are Class B.