On average, listings lease in the $40's per square foot per year. The East LA region is going through a a rise in rates. In the last 3 months, the median rate increased $47 per sqft per year.
In the last 90 days, 22 listings have been made available, which means spaces are probably going fast. You'll want to be prepared to make an offer immediately. About 114% of the listings in the East LA are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 5,500 sqft, there are still 0 leases below 2,000 sqft. Most buildings in this market are approximately 2 stories. Most buildings in this region were built in 1957 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this area. Most of the residents of East LA work from home. Commuting close to 30 minutes a day is the norm for those who opt to reside in this part of town.