Most listings are in the $20's per square foot per year. The Lancaster region is going through a decrease in rates. In the last 3 months, the median rate fell $1 per sqft per year. That's a 4% decline in rent.
Compared to the rest of the Metropolitan Los Angeles market, the Lancaster submarket has smaller rates, so you should have no trouble finding a great deal in this undervalued submarket.
In the last 90 days, 16 listings have been posted online, which means spaces most likley are going fast. You'll want to be prepared to make an offer immediately. About 6% of the available space in the Lancaster are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,350 sqft. Most buildings in this market are around 1 stories. Most buildings in this area were built in 1987 and are Class B.