On average, listings lease in the $20's per square foot per year. The Lancaster region is experiencing a a boost in rates. In the last 3 months, the median rate increased $21 per sqft per year.
Compared to the rest of the Metropolitan Los Angeles market, the Lancaster submarket has lower rates, so you should have no trouble finding a great deal in this undervalued region.
In the last 90 days, 16 listings have been made available, which means listings most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. About 106% of the listings in the Lancaster are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,350 sqft. Most buildings in this area are around 1 floors. Most buildings in this region were built in 1987 and are Class B.