The typical asking rate per listing is in the $20's per square foot per year. The Nogales region is going through a a boost in rates. In the last 3 months, the median rate went up $21 per sqft per year.
In the last 90 days, 2 listings have been posted online, which means office spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,300 sqft.