Most listings are in the $20's per square foot per year. The Appleton submarket is seeing a a boost in rates. In the last 3 months, the median rate rose $25 per sqft per year.
In the last 90 days, 18 listings have been listed, which means leases most likley are going fast. You'll want to be prepared to tour spaces as quick as possible. About 83% of the available space in the Appleton are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,500 sqft. Most buildings in this area are approximately 1 stories. Most buildings in this region were built in 1947 and are Class A.