On average, listings lease in the $10's per square foot per year. The Salem region is experiencing a an increase in rates. In the last 3 months, the median rate rose $18 per sqft per year.
In the last 90 days, 8 listings have been listed, which means spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 88% of the listings in the Salem are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 48,580 sqft, there are still 0 leases below 2,000 sqft. Most properties in this region are around 2 floors. Most buildings in this area were built in 1982 and are Class B.