Most listings are in the $20's per square foot per year. The Old Southwest region is going through a a boost in rates. In the last 3 months, the median rate rose $2 per sqft per year. That's a 12% rise in rent.
In the last 90 days, 2 listings have been made available, which means leases most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 5,500 sqft, there are still 0 leases below 2,000 sqft. Most buildings in this area are around 2 floors. Most buildings in this market were built in 1925 and are Class B.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Waste services is the dominant industry in this area. Most of the residents of Old Southwest work from home. Commuting under 5 minutes a day is the norm for those who opt to reside in this part of town.