Most listings are in the $20's per square foot per year. The East Stroudsburg submarket is going through a a rise in rates. In the last 3 months, the median rate went up $30 per sqft per year.
In the last 90 days, 8 listings have been listed, which means new availabilities most likley are leasing quickly. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 980 sqft. Most properties in this area are around 2 stories. Most buildings in this area were built in 1950 and are Class B.