Compared to the rest of the New York City market, the SoHo region has greater rates, and you'll have to negotiate above asking rent to be in this hot submarket.
In the last 90 days, 150 listings have come on the market, so you'll want to check back regularly for new listings. About 10% of the listings in the SoHo are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
Even though the median size is 5,000 sqft, there are still 0 spaces below 2,000 sqft. Most properties in this region are approximately 5 floors. Most buildings in this area were built in 1910 and are Class B.
This region is fairly equally mixed residential and commercial. Utilities is the dominant industry in this area. Most of the folk of SoHo work from home. Commuting around 20 minutes a day is the norm for those who opt to reside in this part of town.