Most listings are in the $0's per square foot per year. The San Mateo submarket is going through a decrease in rates. In the last 3 months, the median rate decreased $16 per sqft per year. That's a 100% decrease in rent.
In the last 90 days, 9 listings have come on the market, which means new availabilities most likley are going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around sqft. Most buildings in this area are approximately 1 floors. Most buildings in this market were built in 1982 and are Class Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this market. Most of the folk of San Mateo work from home. Commuting approximately 20 minutes a day is the norm for those who opt to reside in this part of town.