Most listings are in the $20's per square foot per year. The Holly Springs submarket is seeing a decline in rates. In the last 3 months, the median rate fell $3 per sqft per year. That's a 10% decrease in rent.
Compared to the rest of the The Triangle market, the Holly Springs region has less expensive rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 17 listings have been listed, which means listings most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,200 sqft. Most buildings in this area were built in 2007 and are Class B.