Most listings are in the $20's per square foot per year. The Rochester region is going through a an increase in rates. In the last 3 months, the median rate increased $1 per sqft per year. That's a 8% rise in rent.
In the last 90 days, 63 listings have come on the market, so you'll want to check back regularly for new listings. About 3% of the office spaces in the Rochester are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,220 sqft. Most buildings in this area are close to 2 floors. Most buildings in this area were built in 1989 and are Class B.