On average, listings lease in the $20's per square foot per year. The Frederick region is experiencing a a boost in rates. In the last 3 months, the median rate went up $3 per sqft per year. That's a 14% rise in rent.
Compared to the rest of the Washington D.C. market, the Frederick submarket has smaller rates, so you should have no trouble finding a great deal in this depreciated region.
In the last 90 days, 65 listings have been listed, so you'll want to check back regularly for new listings. About 18% of the available leases in the Frederick are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,980 sqft. Most properties in this market are around 2 floors. Most buildings in this market were built in 1986 and are Class A.