On average, listings lease in the $20's per square foot per year. The Medford region is going through a an increase in rates. In the last 3 months, the median rate increased $11 per sqft per year. That's a 67% rise in rent.
Compared to the rest of the Greater Boston market, the Medford region has greater rates, and you'll need to make a great offer to be in this hot submarket.
In the last 90 days, 14 listings have been posted online, which means new availabilities most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 7% of the listings in the Medford are subleases, so you will probably have to focus your search on direct office leases. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 700 sqft. Most properties in this market are close to 5 floors. Most buildings in this area were built in 1990 and are Class A.