In the last 90 days, 30 listings have been posted online, which means office spaces are probably going fast. You'll want to be prepared to make an offer immediately. About 3% of the listings in the Mission are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 3,400 sqft, there are still 0 spaces below 2,000 sqft. Most properties in this market are around 2 stories. Most buildings in this region were built in 1972 and are Class B.