Most listings are in the $20's per square foot per year. The Manhattan region is experiencing a decrease in rates. In the last 3 months, the median rate decreased $14 per sqft per year. That's a 38% decrease in rent.
In the last 90 days, 10 listings have come on the market, which means new availabilities might be going fast. You'll want to be prepared to make an offer immediately. About 10% of the available leases in the Manhattan are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 390 sqft. Most properties in this market are close to 1 floors. Most buildings in this market were built in 1984 and are Class A.