Most listings are in the $20's per square foot per year. The Edwardsville region is going through a decline in rates. In the last 3 months, the median rate fell $5 per sqft per year. That's a 18% decline in rent.
In the last 90 days, 50 listings have been listed, so you'll want to check back regularly for new listings. About 6% of the available space in the Edwardsville are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,300 sqft. Most buildings in this region are around 2 stories. Most buildings in this market were built in 2000 and are Class A.