Compared to the rest of the Chicagoland market, the South Loop region has more expensive rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 21 listings have been made available, which means new availabilities are probably going fast. You'll want to be prepared to tour spaces as quick as possible. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 3,350 sqft, there are still 0 new listings below 2,000 sqft. Most properties in this market are close to 4 floors. Most buildings in this market were built in 1922 and are Class B.