Compared to the rest of the Chicagoland market, the DePaul submarket has higher rates, and you'll have to negotiate above asking rent to be in this hot region.
In the last 90 days, 4 listings have been made available, which means spaces most likley are going fast. You'll want to be prepared to make an offer immediately. About 600% of the office spaces in the DePaul are subleases, so you might be able to sign a shorter term by taking over a previous lease. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 180 sqft. Most buildings in this region are close to 3 stories. Most buildings in this market were built in 1927 and are Class C.