The typical asking rate per listing is in the $20's per square foot per year. The Fort Myers region is experiencing a a boost in rates. In the last 3 months, the median rate increased $2 per sqft per year. That's a 8% rise in rent.
In the last 90 days, 35 listings have come on the market, which means office spaces most likley are going fast. You'll want to be prepared to make an offer immediately. About 3% of the office spaces in the Fort Myers are subleases, so you will probably have to consider a longer term lease. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,270 sqft. Most properties in this market are close to 2 floors. Most buildings in this area were built in 1985 and are Class B.