The typical asking rate per listing is in the $10's per square foot per year. The Pueblo region is going through a a boost in rates. In the last 3 months, the median rate increased $16 per sqft per year.
In the last 90 days, 14 listings have come on the market, which means leases most likley are going fast. You'll want to be prepared to make an offer immediately. About 50% of the available space in the Pueblo are subleases, so you might be able to find a shorter term or below market rent. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
Even though the median size is 3,030 sqft, there are still 0 new listings below 2,000 sqft. Most properties in this area are close to 1 stories. Most buildings in this area were built in 1924 and are Class A.