Compared to the rest of the Denver Metro market, the Littleton region has smaller rates, so you should have no trouble finding a great deal in this discounted region.
In the last 90 days, 16 listings have been posted online, which means spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 13% of the available leases in the Littleton are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 2,150 sqft. Most properties in this region are approximately 2 floors. Most buildings in this area were built in 1983 and are Class B.