On average, listings lease in the $10's per square foot per year. The Santee submarket is going through a a rise in rates. In the last 3 months, the median rate rose $18 per sqft per year.
Compared to the rest of the San Diego market, the Santee region has lower rates, so you should have no trouble finding a great deal in this undervalued region.
In the last 90 days, 2 listings have been made available, which means spaces might be going fast. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 2,700 sqft, there are still 0 leases below 2,000 sqft. Most buildings in this area are approximately 2 floors. Most buildings in this market were built in 1973 and are Class C.