On average, listings lease in the $20's per square foot per year. The Santa Cruz region is seeing a decline in rates. In the last 3 months, the median rate decreased $9 per sqft per year. That's a 26% decrease in rent.
In the last 90 days, 21 listings have been posted online, which means spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. There aren't many listings below 2,000 square feet available, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,670 sqft. Most properties in this market are close to 2 floors. Most buildings in this area were built in 1967 and are Class B.