Most listings are in the $30's per square foot per year. The Santa Cruz region is going through a an increase in rates. In the last 3 months, the median rate increased $16 per sqft per year. That's a 76% increase in rent.
In the last 90 days, 9 listings have come on the market, which means office spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About 100% of the office spaces in the Santa Cruz are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,210 sqft. Most properties in this market are approximately 1 stories. Most buildings in this area were built in 1967 and are Class A.