On average, listings lease in the $20's per square foot per year. The Santa Clarita region is seeing a a rise in rates. In the last 3 months, the median rate rose $2 per sqft per year. That's a 6% rise in rent.
Compared to the rest of the Metropolitan Los Angeles market, the Santa Clarita region has less expensive rates, so you should have no trouble finding a great deal in this undervalued submarket.
In the last 90 days, 62 listings have been posted online, so you'll want to check back regularly for new listings. About 2% of the office spaces in the Santa Clarita are subleases, so you will probably need to sign a longer term lease with the landlord directly. There aren't many listings below 2,000 square feet on the market, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around 1,500 sqft. Most buildings in this region are around 2 floors. Most buildings in this market were built in 2003 and are Class A.