Most listings are in the $20's per square foot per year. The Lower East region is experiencing a a rise in rates. In the last 3 months, the median rate rose $24 per sqft per year.
In the last 90 days, 14 listings have been listed, which means leases are probably leasing quickly. You'll want to be prepared to make an offer immediately. About 7% of the listings in the Lower East are subleases, so you will probably need to consider the implications of signing a direct lease with the building. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
Even though the median size is 5,700 sqft, there are still 0 spaces below 2,000 sqft. Most properties in this area are around 2 floors. Most buildings in this area were built in 1989 and are Class A.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Health care is the dominant industry in this market. Commute by walking is the most popular way to get to work amongst Lower East residents. Commuting between 30 and 45 minutes a day is the norm for those who opt to reside in this part of town.